3,5-二氯-4-氟三氟甲苯合成路线 (共 7 条)
反应条件
potassium fluoride; tetra-phenylphosphonium bromide in sulfolane T=100 - 190°C; P=75.0075 Torr; 15 h; Product distribution / selectivity;
参考文献
WO2008/113660 A1, ;
Page/Page column 11 ;
反应条件
sodium nitrite in hydrogenchloride; water
反应条件
tetraphenylphosphonium hydrogendifluoride 2 h; Heating;
参考文献
Brown, S. J.; Clark, J. H.
Journal of Fluorine Chemistry, 1985 , vol. 30, p. 251 - 258
反应条件
sulfuric acid T=120°C;
参考文献
Sanofi-Aventis
Patent: US2005/153963 A1, 2005 ;
Location in patent: Page/Page column 5 ;
US 20050153963 A1
反应条件
hydrazine in tetrahydrofuran T=25°C; 24 h;
参考文献
WO2008/113660 A1, ;
Page/Page column 12-13 ;
反应条件
hydrazine in toluene T=110°C; 24 h; Product distribution / selectivity;
参考文献
BASF SE
Patent: WO2008/113661 A2, 2008 ;
Location in patent: Page/Page column 10 ;
反应条件
hydrogenchloride; nitrogen in diethyl ether; pentane
参考文献
Occidental Chemical Corporation
Patent: US5196593 A1, 1993 ;