3-(2-氧代吡咯烷)丙酸合成路线 （共 8 条）
反应条件
1: With sodium hydroxide; water in 1,4-dioxane 5 h; Heating / reflux; 2: With hydrogenchloride in 1,4-dioxane; water
参考文献
Agouron Pharmaceuticals, Inc.
Patent: US2005/176701 A1, 2005 ;
Location in patent: Page/Page column 22-23 ;
US 20050176701 A1
参考文献
Bulletin of the Chemical Society of Japan, , vol. 36, p. 179,181
Nippon Kagaku Zasshi, , vol. 77, p. 599,601
Chem.Abstr., , p. 9070
反应条件
sodium hydroxide; water
参考文献
Justus Liebigs Annalen der Chemie, , vol. 596, p. 1,211
反应条件
1: aqueous Ba(OH)2 2: 160 - 165 °C View Scheme
参考文献
Nippon Kagaku Zasshi, , vol. 77, p. 599,601
Chem.Abstr., , p. 9070
反应条件
2: aqueous HCl 3: 160 - 165 °C View Scheme
参考文献
Nippon Kagaku Zasshi, , vol. 77, p. 599,601
Chem.Abstr., , p. 9070
反应条件
1: aqueous HCl 2: 160 - 165 °C View Scheme
参考文献
Nippon Kagaku Zasshi, , vol. 77, p. 599,601
Chem.Abstr., , p. 9070
反应条件
1: acetonitrile 2: hydrogen chloride 3: water; NaOH-solution View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 596, p. 1,211
反应条件
1: 150 °C 2: hydrogen chloride 3: water; NaOH-solution View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 596, p. 1,211
