3-氯-1,2-苯代异噻唑合成路线 （共 24 条）
反应条件
in chlorobenzene; paraffin oil
参考文献
Bayer Aktiengesellschaft
Patent: US5883258 A1, 1999 ;
参考文献
US4590196 A1, ;
US 4590196 A
反应条件
1: Cl2 / CH2Cl2 2: concd NH4OH / CH2Cl2 / 1 h 3: 77 percent / POCl3 / 3.5 h / 20 - 120 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 3 p. 359 - 369
反应条件
1: 71 percent / SOCl2 / dimethylformamide; toluene / 18 h / 75 °C 2: Cl2 / CH2Cl2 3: concd NH4OH / CH2Cl2 / 1 h 4: 77 percent / POCl3 / 3.5 h / 20 - 120 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 3 p. 359 - 369
反应条件
1: concd NH4OH / CH2Cl2 / 1 h 2: 77 percent / POCl3 / 3.5 h / 20 - 120 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 29, # 3 p. 359 - 369
反应条件
tributyl-amine; trichlorophosphate T=20 - 115°C;
参考文献
Tanikawa, Hiroharu; Ishii, Kazuhiro; Kubota, Shun; Sasanuma, Takashi; Yagai, Shiki; Kitamura, Akihide; Karatsu, Takashi
Heterocycles, 2010 , vol. 81, # 3 p. 659 - 674
反应条件
1: pentyl nitrile 2: 35 percent / tetrahydrofuran / 0.5 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2141 - 2144
反应条件
in tetrahydrofuran 0.5 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2141 - 2144
参考文献
Zeitschrift fuer Chemie (Stuttgart, Germany), , vol. 8, # 5 p. 170 - 171
反应条件
1: 56.4 percent / 12 h / 120 °C 2: 87 percent / K2CO3, KI / dimethylformamide / 3 h / 90 - 100 °C 3: 86.2 percent / hydrazine hydrate / methanol / 2.5 h / Heating View Scheme
参考文献
Ishizumi; Kojima; Antoku; Saji; Yoshigi
Chemical and Pharmaceutical Bulletin, 1995 , vol. 43, # 12 p. 2139 - 2151
