1: 2-amino-3-methyl benzoic acid With hydrogenchloride; sodium hydroxide; sodium nitrite in water
Cooling with ice;
2: potassium ethylxanthate in water
T=80°C;
3: With hydrogenchloride in water
T=20°C;
参考文献
Institute Of Medicinal Molecular Design, Inc.; ShionogiandCo., Ltd.
Patent: EP2208728 A1, 2010 ;
Location in patent: Page/Page column 46 ;
Guise, G. Bruce; Ollis, W. David; Peacock, Judith A.; Stephanatou, Julia Stephanidou; Stoddart, J. Fraser
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , # 8 p. 1637 - 1648
Guise, Bruce G.; Ollis, David W.; Peacock, Judith A.; Stephanatou, Julia Stephanidou; Stoddart, Fraser J.
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