2-[(三甲基硅基)乙炔基]苯甲醛合成路线 （共 35 条）
反应条件
1: With bis-triphenylphosphine-palladium(II) chloride; triethylamine T=20°C; Sonogashira coupling; 0.25 h; Inert atmosphere; 2: With copper(l) iodide T=50°C; Sonogashira coupling; 2.5 h; Inert atmosphere;
参考文献
Yoshida, Kazuhiro; Nishii, Kana; Kano, Yuto; Wada, Shiro; Yanagisawa, Akira
Journal of Organic Chemistry, 2014 , vol. 79, # 9 p. 4231 - 4239
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide Heating;
参考文献
Iwasawa, Nobuharu; Otsuka, Maiko; Yamashita, Satomi; Aoki, Masao; Takaya, Jun
Journal of the American Chemical Society, 2008 , vol. 130, # 20 p. 6328 - 6329
反应条件
manganese(IV) oxide in acetonitrile
参考文献
Rosillo, Marta; Dominguez, Gema; Casarrubios, Luis; Amador, Ulises; Perez-Castells, Javier
Journal of Organic Chemistry, 2004 , vol. 69, # 6 p. 2084 - 2093
反应条件
1: 100 percent / Pd(PPh3)2Cl2; CuI; n-BuNH2 / toluene 2: 99 percent / MnO2 / acetonitrile View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 6 p. 2084 - 2093
反应条件
1: 100 percent / Pd(PPh3)2Cl2; CuI; n-BuNH2 / toluene 2: 99 percent / MnO2 / acetonitrile View Scheme
参考文献
Journal of Organic Chemistry, , vol. 69, # 6 p. 2084 - 2093
反应条件
sodium tetrahydroborate in methanol T=0 - 20°C; 20 h; Inert atmosphere;
参考文献
Ackermann, Martin; Bucher, Janina; Rappold, Melissa; Graf, Katharina; Rominger, Frank; Hashmi, A. Stephen K.
Chemistry - An Asian Journal, 2013 , vol. 8, # 8 p. 1786 - 1794
反应条件
methanol; potassium carbonate T=20°C;
参考文献
Dell'Acqua, Monica; Facoetti, Diego; Abbiati, Giorgio; Rossi, Elisabetta
Synthesis, 2010 , # 14 art. no. Z06110SS, p. 2367 - 2378
反应条件
1: Methyltriphenylphosphonium bromide With n-butyllithium in tetrahydrofuran T=0°C; 0.5 h; 2: 2-(2-trimethylsilyleth-1-yn-1-yl)benzaldehyde in tetrahydrofuran T=20°C; 4 h;
参考文献
Madhushaw, Reniguntala J.; Lin, Ming-Yuan; Abu Sohel, Shariar Md.; Liu, Rai-Shung
Journal of the American Chemical Society, 2004 , vol. 126, # 22 p. 6895 - 6899
反应条件
1: Ph3P(1+)MeI With n-butyllithium in tetrahydrofuran; hexane T=0°C; 0.5 h; Inert atmosphere; 2: 2-(2-trimethylsilyleth-1-yn-1-yl)benzaldehyde in tetrahydrofuran; hexane T=20°C; 0.5 h; Inert atmosphere;
参考文献
Vasu, Dhananjayan; Hung, Hsiao-Hua; Bhunia, Sabyasachi; Gawade, Sagar Ashok; Das, Arindam; Liu, Rai-Shung
Angewandte Chemie - International Edition, 2011 , vol. 50, # 30 p. 6911 - 6914
反应条件
1: 79 percent / NaH / tetrahydrofuran / 12 h / 26 °C 2: 85.6 percent / Bu4NF / tetrahydrofuran / 10 h / 27 °C 3: 88 percent / TpRu(PPh3)(CH3CN)2PF6 / toluene / 6 h / 110 °C View Scheme
参考文献
Shen, Hung-Chin; Pal, Sitaram; Lian, Jian-Jou; Liu, Rai-Shung
Journal of the American Chemical Society, 2003 , vol. 125, # 51 p. 15762 - 15763
