1,4-二羟基-2-萘甲酸甲酯合成路线 (共 14 条)
反应条件
1: 1.) iPr2NLi, HMPA / 1.) THF, -78 deg C, 2.) THF, RT, 8 h 2: 5 percent / NCS, H2O / acetone / 3 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 44, # 10 p. 1785 - 1789
反应条件
acetic acid; 3,4,5-trimethoxyphenylboronic acid in toluene 8 h; RefluxInert atmosphere;
参考文献
Idhayadhulla, Akber; Xia, Likai; Lee, Yong Rok; Kim, Sung Hong; Wee, Young-Jung; Lee, Chong-Soon
Bioorganic Chemistry, 2014 , vol. 52, p. 77 - 82
反应条件
1: BF3*Et2O / tetrahydrofuran / 64 h / Heating 2: 81 percent / DDQ / toluene / 18 h / Heating View Scheme
参考文献
Ho, Li-Kang; Yu, Hsi-Jung; Ho, Chen-Ta; Don, Ming-Jaw
Journal of the Chinese Chemical Society, 2001 , vol. 48, # 1 p. 77 - 79
反应条件
magnesium sulfate; silver(l) oxide in diethyl ether
T=20°C; 0.5 h;
参考文献
Jacobs, Jan; Claessens, Sven; Mavinga Mbala, Blaise; Huygen, Kris; De Kimpe, Norbert
Tetrahedron, 2009 , vol. 65, # 6 p. 1193 - 1199