1-N-BOC-4-(4-溴苯基)哌啶合成路线 （共 5 条）
反应条件
in dichloromethane T=0 - 20°C;
参考文献
SCHERING CORPORATION; MANSOOR, Umar, Faruk; REDDY, Panduranga, Adulla; SIDDIQUI, M., Arshad
Patent: WO2010/17060 A1, 2010 ;
Location in patent: Page/Page column 31 ;
WO 2010/017060 A1
反应条件
triethylamine in dichloromethane T=20°C; 1.16667 h;
参考文献
WO2009/7390 A2, ;
Page/Page column 96 ;
WO 2009/007390 A2
反应条件
1: With sodium hydride in N,N-dimethyl-formamide 0.25 h; 2: With di-tert-butyl dicarbonate in N,N-dimethyl-formamide 18 h;
参考文献
WO2007/126957 A2, ;
Page/Page column 101 ;
WO 2007/126957 A2
反应条件
caesium carbonate in 1,4-dioxane T=110°C; 18 h; Inert atmosphereSchlenk technique;
参考文献
Allwood, Daniel M.; Blakemore, David C.; Brown, Alan D.; Ley, Steven V.
Journal of Organic Chemistry, 2014 , vol. 79, # 1 p. 328 - 338
反应条件
hydrogenchloride in ethyl acetate T=20°C; 5 h;
参考文献
MITSUBISHI PHARMA CORPORATION; SANOFI-SYNTHELABO
Patent: WO2004/85408 A1, 2004 ;
Location in patent: Page 294 ;
WO 2004/085408 A1
