1-(异丙基氨基)-3-苯氧基-2-丙醇合成路线 （共 23 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol
P=760 Torr; 15 h; Ambient temperature;
参考文献
Baeckvall, Jan-E.; Bystroem, Styrbjoern E.
Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 1126 - 1128
反应条件
calcium trifluoromethane sulfonate in acetonitrile
T=20°C; 0.5 h;
参考文献
Cepanec, Ivica; Litvic, Mladen; Mikuldas, Hrvoje; Bartolincic, Anamarija; Vinkovic, Vladimir
Tetrahedron, 2003 , vol. 59, # 14 p. 2435 - 2439
反应条件
1: 1.) (C6H5CN)2PdCl2, 2.) CH3COOAg, (CH3COO)4Pb / 1.) THF, -50 deg C, 1 h, 2.) THF, -50 deg C to room temperature, 2.5 h
2: 98 percent / KOH / methanol / 0.5 h / Heating
3: 75 percent / H2 / 10percent Pd/C / ethanol / 15 h / 760 Torr / Ambient temperature
View Scheme
参考文献
Baeckvall, Jan-E.; Bystroem, Styrbjoern E.
Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 1126 - 1128
反应条件
1: 98 percent / KOH / methanol / 0.5 h / Heating
2: 75 percent / H2 / 10percent Pd/C / ethanol / 15 h / 760 Torr / Ambient temperature
View Scheme
参考文献
Baeckvall, Jan-E.; Bystroem, Styrbjoern E.
Journal of Organic Chemistry, 1982 , vol. 47, # 6 p. 1126 - 1128
反应条件
1: 60 percent / K2CO3 / acetone / 12 h / Heating
2: ethanol / 4 h / Heating
View Scheme
参考文献
Erhardt; Woo; Gorczynski; Anderson
Journal of Medicinal Chemistry, 1982 , vol. 25, # 12 p. 1402 - 1407
反应条件
1: NaOEt / ethanol / Heating
2: H2, HCl / Pd-C / ethanol; diethyl ether
View Scheme
参考文献
Villa,L. et al.
Farmaco, Edizione Scientifica, 1969 , vol. 24, p. 349 - 357
参考文献
GIST-BROCADES N.V.; SHELL INTERNATIONALE RESEARCH, MAATSCHAPPIJ B.V.
Patent: EP193227 A1, 1986 ;
反应条件
1: 70 percent / potassium ferrate / CH2Cl2 / 24 h / Ambient temperature
2: 80 percent / H(1+) / 24 h / Ambient temperature
3: TiI4, LiAlH4 / tetrahydrofuran
4: 45 percent / tetrahydrofuran
View Scheme
参考文献
Bermudez; Del Campo; Sinisterra; Llama
Tetrahedron Letters, 1997 , vol. 38, # 23 p. 4137 - 4140
反应条件
1: TiI4, LiAlH4 / tetrahydrofuran
2: 45 percent / tetrahydrofuran
View Scheme
参考文献
Bermudez; Del Campo; Sinisterra; Llama
Tetrahedron Letters, 1997 , vol. 38, # 23 p. 4137 - 4140
反应条件
1: 80 percent / H(1+) / 24 h / Ambient temperature
2: TiI4, LiAlH4 / tetrahydrofuran
3: 45 percent / tetrahydrofuran
View Scheme
参考文献
Bermudez; Del Campo; Sinisterra; Llama
Tetrahedron Letters, 1997 , vol. 38, # 23 p. 4137 - 4140
