1-(乙氧羰基)-3-环戊烯-1-甲酸合成路线 （共 11 条）
反应条件
1: With Grubb's 2nd generation catalyst in water
T=20°C; 6 h;
2: With pig liver esterase; water; sodium chloride in tert-butyl alcohol
T=20°C; 102 h; Enzymatic reaction;
参考文献
Tenbrink, Katharina; Sessler, Miriam; Schatz, Juergen; Groeger, Harald
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 13 p. 2363 - 2367
反应条件
potassium hydroxide in ethanol
20 h; Ambient temperature;
参考文献
Paulsen, Hans; Maass, Uwe
Chemische Berichte, 1981 , vol. 114, # 1 p. 346 - 358
反应条件
1: Grubb's 2nd generation catalyst / water / 6 h / 20 °C
2: pig liver esterase; water; sodium chloride / 25 h / 20 °C / Enzymatic reaction
View Scheme
参考文献
Tenbrink, Katharina; Sessler, Miriam; Schatz, Juergen; Groeger, Harald
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 13 p. 2363 - 2367
反应条件
1: Grubb's 2nd generation catalyst / water / 6 h / 20 °C
2: pig liver esterase; water; sodium chloride / 12 h / 20 °C / Enzymatic reaction
View Scheme
参考文献
Tenbrink, Katharina; Sessler, Miriam; Schatz, Juergen; Groeger, Harald
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 13 p. 2363 - 2367
反应条件
pig liver esterase; water; sodium chloride
T=20°C; 25 h; Enzymatic reaction;
参考文献
Tenbrink, Katharina; Sessler, Miriam; Schatz, Juergen; Groeger, Harald
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 13 p. 2363 - 2367
反应条件
pig liver esterase; water; sodium chloride
T=20°C; 12 h; Enzymatic reaction;
参考文献
Tenbrink, Katharina; Sessler, Miriam; Schatz, Juergen; Groeger, Harald
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 13 p. 2363 - 2367
反应条件
pig liver esterase; water; sodium chloride
T=20°C; 42 h; Enzymatic reaction;
参考文献
Tenbrink, Katharina; Sessler, Miriam; Schatz, Juergen; Groeger, Harald
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 13 p. 2363 - 2367
反应条件
1: 89.4 percent / SOCl2 / toluene / 2 h / Heating
2: NaN3 / H2O; acetone / 0.5 h / 0 °C
3: benzene / 0.5 h / Heating
View Scheme
参考文献
Paulsen, Hans; Maass, Uwe
Chemische Berichte, 1981 , vol. 114, # 1 p. 346 - 358
反应条件
1: (COCl)2; DMF / CH2Cl2 / 100 °C
2: NaN3 / acetone; H2O / 0.5 h / 3 - 6 °C
3: 3 Angstroem MS / 2-methyl-propan-2-ol / 2 h / Heating
4: 16.1 g / SnCl4 / 1 h / Heating
View Scheme
参考文献
Hodgson, David M.; Thompson, Alison J.; Wadman, Sjoerd; Keats, Clare J.
Tetrahedron, 1999 , vol. 55, # 35 p. 10815 - 10834
反应条件
thionyl chloride in toluene
2 h; Heating;
参考文献
Paulsen, Hans; Maass, Uwe
Chemische Berichte, 1981 , vol. 114, # 1 p. 346 - 358
