3-氟-4-硝基-N-氧化吡啶合成路线 (共 5 条)
反应条件
nitric acid in sulfuric acid
参考文献
Siev, Daniel Vanna; Semple, Joseph Edward; Komandla, Mallareddy; Reiner, John Eugene; Kemp, Scott Jeffrey
Patent: US2003/92679 A1, 2003 ;
US 20030092679 A1
反应条件
1: acetic acid; sulfuric acid; dihydrogen peroxide / water / 24 h / 85 °C / |Inert atmosphere; |Reflux 2: sulfuric acid; nitric acid / 4 h / 90 °C View Scheme
反应条件
ammonium hydroxide in water
参考文献
Siev, Daniel Vanna; Semple, Joseph Edward; Komandla, Mallareddy; Reiner, John Eugene; Kemp, Scott Jeffrey
Patent: US2003/92679 A1, 2003 ;
US 20030092679 A1
反应条件
titanium in tetrahydrofuran 0.25 h; Ambient temperature; Yield given;
参考文献
Maryanoff; McComsey; Ho; Shank; Dubinsky
Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 3 p. 333 - 338
反应条件
potassium carbonate in acetone; acetonitrile
参考文献
Warner-Lambert Company
Patent: US4179563 A1, 1979 ;