反应条件
1: 92 percent / Et3SIH, TFA 2: 1.) n-BuLi 3: 76 percent / 2 N aq. NaOH / ethanol 4: 1.) TMSCl, NaI, Dabco, 2.) 6 N aq. HCl / 1.) CH3CN, reflux, 5 h, 2.) 100 deg C, 4 h 5: 95 percent / H2, NaOAc / Pd/C / methanol 6: 87 percent / t-BuOK / 1,2-dimethoxy-ethane / 48 h / Heating 7: 59 percent / Pd(OAc)2, Bu4N(1+)*Br(1-), KOAc / dimethylformamide / 3 h / 90 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 114, # 27 p. 10971 - 10972
