1: 50 percent / N,N-dimethyl-acetamide / 120 h / 20 - 25 °C 2: 79 percent / aq. NaOH / methanol / 24 h / 20 - 25 °C View Scheme

magnesium oxide in N,N-dimethyl acetamide T=90 - 100°C; 16 h;

calcium carbonate in N-methyl-acetamide; diethyl ether; ethanol; water

1: 52 percent / N,N-dimethyl-acetamide / 1.) 25 deg C, 18 h, 2.) 60 deg C, 6 h, 3.) 80 deg C, 1 h 2: 81 percent / 1N aq. NaOH / methanol / 1.) 25 deg C, 18 h, 2.) reflux, 1 h View Scheme