3-氨基-4-苯氧基苯甲醚合成路线 （共 10 条）
反应条件
1: 82 percent / pyridine / 1 h / 20 °C 2: 90 percent / AlCl3; HCl / nitrobenzene / 10 h / 25 - 30 °C 3: 91 percent / acetone / 3 h 4: 95 percent / NaI; AlCl3 / acetonitrile / 3 h / 20 °C View Scheme
参考文献
Inaba, Takihiro; Tanaka, Keiichi; Takeno, Ryuko; Nagaki, Hideyoshi; Yoshida, Chosaku; Takano, Shuntaro
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 1 p. 131 - 139
反应条件
1: 82 percent / pyridine / 1 h / 20 °C 2: 90 percent / AlCl3; HCl / nitrobenzene / 10 h / 25 - 30 °C 3: 91 percent / acetone / 3 h View Scheme
参考文献
Inaba, Takihiro; Tanaka, Keiichi; Takeno, Ryuko; Nagaki, Hideyoshi; Yoshida, Chosaku; Takano, Shuntaro
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 1 p. 131 - 139
反应条件
1: 82 percent / pyridine / 1 h / 20 °C 2: 90 percent / AlCl3; HCl / nitrobenzene / 10 h / 25 - 30 °C 3: 91 percent / acetone / 3 h 4: 95 percent / NaI; AlCl3 / acetonitrile / 3 h / 20 °C 5: 87 percent / dimethylformamide / 8 h / 15 °C View Scheme
参考文献
Inaba, Takihiro; Tanaka, Keiichi; Takeno, Ryuko; Nagaki, Hideyoshi; Yoshida, Chosaku; Takano, Shuntaro
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 1 p. 131 - 139
反应条件
hydrogenchloride; iron in ethanol
T=65 - 70°C; Reduction; 0.333333 h;
参考文献
Inaba, Takihiro; Tanaka, Keiichi; Takeno, Ryuko; Nagaki, Hideyoshi; Yoshida, Chosaku; Takano, Shuntaro
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 1 p. 131 - 139
反应条件
1: 84 percent / potassium tert-butoxide / dimethylformamide / 4 h / 110 °C
2: 72 percent / 4N aq. HCl; Fe / ethanol / 0.33 h / 65 - 70 °C
View Scheme
参考文献
Inaba, Takihiro; Tanaka, Keiichi; Takeno, Ryuko; Nagaki, Hideyoshi; Yoshida, Chosaku; Takano, Shuntaro
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 1 p. 131 - 139
反应条件
1: 84 percent / potassium tert-butoxide / dimethylformamide / 4 h / 110 °C
2: 72 percent / 4N aq. HCl; Fe / ethanol / 0.33 h / 65 - 70 °C
View Scheme
参考文献
Inaba, Takihiro; Tanaka, Keiichi; Takeno, Ryuko; Nagaki, Hideyoshi; Yoshida, Chosaku; Takano, Shuntaro
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 1 p. 131 - 139
反应条件
1: Cu / 195 °C
2: Fe, AcOH / H2O; methanol
View Scheme
参考文献
Forrest,J.
Journal of the Chemical Society, 1960 , p. 581 - 588
反应条件
1: Cu / 195 °C
2: Fe, AcOH / H2O; methanol
View Scheme
参考文献
Forrest,J.
Journal of the Chemical Society, 1960 , p. 581 - 588
反应条件
1: (i) aq. HBr, NaNO2, (ii) CuBr, aq. HBr
2: Cu, 4-methoxy-phenol <K salt> / 220 - 230 °C
View Scheme
参考文献
Forrest,J.
Journal of the Chemical Society, 1960 , p. 581 - 588
反应条件
1: 82 percent / pyridine / 1 h / 20 °C
2: 84 percent / aluminum chloride / CH2Cl2 / 1 h / 15 - 20 °C
3: 70 percent aq. HClO4 / 1 h / 20 °C
4: H2O / 0.08 h / Heating
View Scheme
参考文献
Inaba, Takihiro; Tanaka, Keiichi; Takeno, Ryuko; Nagaki, Hideyoshi; Yoshida, Chosaku; Takano, Shuntaro
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 1 p. 131 - 139
