1-甲基-5-氰基吡啶-2(1H)-酮合成路线 （共 8 条）
反应条件
trichlorophosphate
T=120 - 125°C; 2 h;
参考文献
Buurman; Van der Plas
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 4 p. 1015 - 1018
反应条件
1: pyridine / dichloromethane / 20 h / 20 °C
2: dimethylsulfoxide-d6 / 25 °C
View Scheme
参考文献
Topczewski, Joseph J.; Quinn, Daniel M.
Organic Letters, 2013 , vol. 15, # 5 p. 1084 - 1087
反应条件
1: 75 percent / potassium permanganate, NH3(l) / 4 h / -33 °C
2: 90 percent / aq. KOH / 4 h / Heating
View Scheme
参考文献
Buurman; Van der Plas
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 4 p. 1015 - 1018
反应条件
1: 80 percent / potassium permanganate, NH3(l) / 4 h / -33 °C
2: 60 percent / POCl3 / 2 h / 120 - 125 °C
View Scheme
参考文献
Buurman; Van der Plas
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 4 p. 1015 - 1018
反应条件
1: 90 percent / aq. KOH / 4 h / Heating
View Scheme
参考文献
Buurman; Van der Plas
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 4 p. 1015 - 1018
参考文献
Chem. Fabr. v. Heyden
Patent: DE596821 , 1933 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 21, p. 514
反应条件
in dimethylsulfoxide-d6
T=25°C; Kinetics; Solvent;
参考文献
Topczewski, Joseph J.; Quinn, Daniel M.
Organic Letters, 2013 , vol. 15, # 5 p. 1084 - 1087
参考文献
Buurman; Van der Plas
Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 4 p. 1015 - 1018
