1,1-二(苯基)-2-(1,2,4-三唑-1-基)乙醇合成路线 （共 6 条）
反应条件
18-crown-6 ether; potassium tert-butylate in tetrahydrofuran
T=-20°C; 4 h;
参考文献
Shimizu, Sumio; Ogata, Masaru
Journal of Organic Chemistry, 1986 , vol. 51, # 20 p. 3897 - 3900
反应条件
sodium hydroxide in various solvent(s)
T=150°C; equilibrium; ΔG(excit.), ΔG, free energy diagram; Thermodynamic data;
参考文献
Bentley, T. William; Jones, Ray V.H.; Wareham, Peter J.
Tetrahedron Letters, 1989 , vol. 30, # 30 p. 4013 - 4016
反应条件
in N-methyl-acetamide; N,N-dimethyl-formamide
参考文献
Imperial Chemical Industries PLC
Patent: US4551469 A1, 1985 ;
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=86°C; 1 h;
参考文献
Bentley, T. William; Jones, Ray V.H.; Wareham, Peter J.
Tetrahedron Letters, 1989 , vol. 30, # 30 p. 4013 - 4016
反应条件
sodium hydroxide in various solvent(s)
T=138°C; 0.25 h;
参考文献
Bentley, T. William; Howle, Lisa M.; Wareham, Peter J.; Jones, Ray V. H.
Tetrahedron, 1992 , vol. 48, # 37 p. 7869 - 7878
反应条件
sodium hydroxide in various solvent(s)
T=138°C; 1 h;
参考文献
Bentley, T. William; Howle, Lisa M.; Wareham, Peter J.; Jones, Ray V. H.
Tetrahedron, 1992 , vol. 48, # 37 p. 7869 - 7878
