鸟嘌呤核糖苷-3’,5’-环磷酸酯合成路线 （共 10 条）
反应条件
1: POCl3 / various solvent(s) / 1 h / 0 °C 2: 0.08 M KOH / acetonitrile; H2O / 0 °C View Scheme
参考文献
Synthesis, , # 1 p. 53 - 54
反应条件
LLC-PK1 guanylate cyclase; 1-methyl-3-isobutyl-xanthine; magnesium chloride in alkaline aq. solution T=37°C; Cyclization; pH=7.6; 0.25 h; Enzyme kinetics; Further Variations:Reagents;
参考文献
Journal of Pharmacology and Experimental Therapeutics, , vol. 273, # 1 p. 16 - 25
反应条件
in water Irradiation; Quantum yield;
参考文献
Angewandte Chemie - International Edition, , vol. 40, # 6 p. 1046 - 1048
反应条件
in water Irradiation; Quantum yieldProduct distribution; Further Variations:irradiation wavelength, irradiation time;
参考文献
Angewandte Chemie - International Edition, , vol. 40, # 6 p. 1046 - 1048
反应条件
in water Irradiation; Quantum yield;
参考文献
Angewandte Chemie - International Edition, , vol. 40, # 6 p. 1046 - 1048
反应条件
in water Irradiation; Quantum yieldProduct distribution; Further Variations:irradiation wavelength, irradiation time;
参考文献
Angewandte Chemie - International Edition, , vol. 40, # 6 p. 1046 - 1048
反应条件
PhotolysisHepes buffer; Conversion of starting material;
参考文献
US2007/249822 A1, ;
Page/Page column 6; Figure 1 ;
反应条件
1: With bromine in formamide T=0°C; 0.5 h; 2: With sodium hydroxide in water; formamide pH=9.0;
参考文献
EP1860114 A1, ;
Page/Page column 5-6 ;
反应条件
cerium(III) chloride; air T=37°C; 0.0833333 h; pH 8;
参考文献
Li, Xinmin; Zhu, Bing; Zhao, Daqing; Ni, Jiazuan
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1996 , vol. 35, # 11 p. 1144 - 1147
反应条件
Lactuca phosphodiesterase in water 0.416667 h; Tris-HCl buffer (pH 6.5); effect of purification stage of phosphodiesterase; relative rate of hydrolysis; Product distribution;
参考文献
Phytochemistry (Elsevier), , vol. 27, # 8 p. 2477 - 2484
