甲基反式-3-氨基环丁烷羧酸酯合成路线 （共 13 条）
反应条件
1: 1 h / Reflux
2: sodium azide / N,N-dimethyl-formamide / 75 h / 100 °C
3: hydrogenchloride; palladium 10 on activated carbon; hydrogen / methanol; water / 3 h / 750.08 Torr
View Scheme
参考文献
Radchenko, Dmytro S.; Tkachenko, Anton; Grygorenko, Oleksandr O.; Komarov, Igor V.
Synthetic Communications, 2011 , vol. 41, # 11 p. 1644 - 1649
反应条件
1: pyridine / 18 h / Reflux
2: thionyl chloride / dichloromethane / 1 h / Reflux
3: 1 h / Reflux
4: sodium azide / N,N-dimethyl-formamide / 75 h / 100 °C
5: hydrogenchloride; palladium 10 on activated carbon; hydrogen / methanol; water / 3 h / 750.08 Torr
View Scheme
参考文献
Radchenko, Dmytro S.; Tkachenko, Anton; Grygorenko, Oleksandr O.; Komarov, Igor V.
Synthetic Communications, 2011 , vol. 41, # 11 p. 1644 - 1649
反应条件
1: sodium azide / N,N-dimethyl-formamide / 75 h / 100 °C
2: hydrogenchloride; palladium 10 on activated carbon; hydrogen / methanol; water / 3 h / 750.08 Torr
View Scheme
参考文献
Radchenko, Dmytro S.; Tkachenko, Anton; Grygorenko, Oleksandr O.; Komarov, Igor V.
Synthetic Communications, 2011 , vol. 41, # 11 p. 1644 - 1649
