3-乙基-4-甲基-3-吡咯啉-2-酮合成路线 （共 16 条）
反应条件
dihydrogen peroxide; sodium hydrogencarbonate in methanol T=20°C;
参考文献
Coffin, Aaron R.; Roussell, Michael A.; Tserlin, Elina; Pelkey, Erin T.
Journal of Organic Chemistry, 2006 , vol. 71, # 17 p. 6678 - 6681
反应条件
hydrogen; acetic anhydride; sodium carbonate; T-1 Raney Nickel 1.) EtOH, 33 deg C, 50 psi, 12 h, 2.) reflux, 4 h; Yield given. Multistep reaction;
参考文献
Journal of the American Chemical Society, , vol. 113, # 21 p. 8024 - 8035
反应条件
1: 80 percent / dimethylformamide / 0 - 5 °C 2: 15 percent / H2; Ac2O / Ra-Ni / 40 °C / 3800 Torr 3: 90 percent / Na2CO3; H2O / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 44, # 26 p. 4853 - 4855
反应条件
sodium tetrahydroborate in ethanol
参考文献
Tipton, Adrianne K.; Lightner, David A.
Monatshefte fur Chemie, 1999 , vol. 130, # 3 p. 425 - 440
反应条件
water; sodium carbonate Heating;
参考文献
Gurjar, Mukund K.; Joshi, Ramesh A.; Chaudhuri, Siddhartha R.; Joshi, Shreerang V.; Barde, Anup R.; Gediya, Lalji K.; Ranade, Prasad V.; Kadam, Suresh M.; Naik, Sanjay J.
Tetrahedron Letters, 2003 , vol. 44, # 26 p. 4853 - 4855
反应条件
1: 65 percent / LiAlH4 / tetrahydrofuran / 0 °C 2: 67 percent / NaHCO3; aq. H2O2 / methanol / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 71, # 17 p. 6678 - 6681
反应条件
1: 53 percent / guanidine / propan-2-ol; tetrahydrofuran / 1 h 2: 97 percent / Br2 / CH2Cl2 / 1 h / 0 °C 3: 81 percent / aq. TFA 4: 95 percent / NaBH4 / ethanol View Scheme
参考文献
Monatshefte fur Chemie, , vol. 130, # 3 p. 425 - 440
反应条件
1: 97 percent / Br2 / CH2Cl2 / 1 h / 0 °C 2: 81 percent / aq. TFA 3: 95 percent / NaBH4 / ethanol View Scheme
参考文献
Monatshefte fur Chemie, , vol. 130, # 3 p. 425 - 440
反应条件
1: 81 percent / aq. TFA 2: 95 percent / NaBH4 / ethanol View Scheme
参考文献
Monatshefte fur Chemie, , vol. 130, # 3 p. 425 - 440
反应条件
pyridine; dihydrogen peroxide T=50 - 60°C;
参考文献
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 282, p. 96,103
