potassium carbonate in methanol 0.166667 h; Ambient temperature;

2: 94 percent / lithium aluminum hydride / diethyl ether / 1.) from -77 deg C to -60 deg C, 2.) -45 deg C, 15 min 3: 96 percent / pyridine / 1.) 0 deg C, 30 min, 2.) RT, 20 h 4: 62 percent / pyridinium p-toluenesulfonate (PPTS) / ethanol / 4 h / 55 °C 5: 55 percent / (Et2N)(Me2N)SF2 / CCl3F / 1.) -70 deg C, 45 min, 2.) RT, 1 h 6: 83 percent / potassium carbonate / methanol / 0.17 h / Ambient temperature View Scheme

1: 55 percent / (Et2N)(Me2N)SF2 / CCl3F / 1.) -70 deg C, 45 min, 2.) RT, 1 h 2: 83 percent / potassium carbonate / methanol / 0.17 h / Ambient temperature View Scheme

1: 96 percent / pyridine / 1.) 0 deg C, 30 min, 2.) RT, 20 h 2: 62 percent / pyridinium p-toluenesulfonate (PPTS) / ethanol / 4 h / 55 °C 3: 55 percent / (Et2N)(Me2N)SF2 / CCl3F / 1.) -70 deg C, 45 min, 2.) RT, 1 h 4: 83 percent / potassium carbonate / methanol / 0.17 h / Ambient temperature View Scheme

1: 62 percent / pyridinium p-toluenesulfonate (PPTS) / ethanol / 4 h / 55 °C 2: 55 percent / (Et2N)(Me2N)SF2 / CCl3F / 1.) -70 deg C, 45 min, 2.) RT, 1 h 3: 83 percent / potassium carbonate / methanol / 0.17 h / Ambient temperature View Scheme

1: 94 percent / lithium aluminum hydride / diethyl ether / 1.) from -77 deg C to -60 deg C, 2.) -45 deg C, 15 min 2: 96 percent / pyridine / 1.) 0 deg C, 30 min, 2.) RT, 20 h 3: 62 percent / pyridinium p-toluenesulfonate (PPTS) / ethanol / 4 h / 55 °C 4: 55 percent / (Et2N)(Me2N)SF2 / CCl3F / 1.) -70 deg C, 45 min, 2.) RT, 1 h 5: 83 percent / potassium carbonate / methanol / 0.17 h / Ambient temperature View Scheme