LATRUNCULIN B合成路线 （共 36 条）
反应条件
ammonium cerium(IV) nitrate in water; acetonitrile
参考文献
Fuerstner, Alois; De Souza, Dominic; Turet, Laurent; Fenster, Michael D. B.; Parra-Rapado, Liliana; Wirtz, Conny; Mynott, Richard; Lehmann, Christian W.
Chemistry - A European Journal, 2007 , vol. 13, # 1 p. 115 - 134
反应条件
water; acetic acid in tetrahydrofuran T=60°C; 2 h;
参考文献
Smith III, Amos B.; Leahy, James W.; Noda, Ichio; Remiszewski, Stacy W.; Liverton, Nigel J.; Zibuck, Regina
Journal of the American Chemical Society, 1992 , vol. 114, # 8 p. 2995 - 3007
反应条件
1: 75 percent / Ba(OH)2*8H2O / tetrahydrofuran; H2O / 3 h 2: 57 percent / aq. HCl / tetrahydrofuran / 20 °C 3: 92 percent / camphor-10-sulfonic acid / 20 °C 4: pyridine / CH2Cl2 / 1 h / -20 °C 5: 45 mg / [15]crown-5 ether / tetrahydrofuran / 20 °C 6: 70 percent / Mo[N-(tBu)(3,5-dimethylphenyl)]3 / toluene / 20 h / 80 °C 7: 100 percent / hydrogen / Lindlar / CH2Cl2 8: 78 percent / aq. cerium ammonium nitrate / acetonitrile / 3 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 1 p. 115 - 134
反应条件
1.1: ozone; Sudan red 7B / methanol 1.2: 94 percent / Me2S / methanol / 24 h / 20 °C 2.1: 75 percent / Ba(OH)2*8H2O / tetrahydrofuran; H2O / 3 h 3.1: 57 percent / aq. HCl / tetrahydrofuran / 20 °C 4.1: 92 percent / camphor-10-sulfonic acid / 20 °C 5.1: pyridine / CH2Cl2 / 1 h / -20 °C 6.1: 45 mg / [15]crown-5 ether / tetrahydrofuran / 20 °C 7.1: 70 percent / Mo[N-(tBu)(3,5-dimethylphenyl)]3 / toluene / 20 h / 80 °C 8.1: 100 percent / hydrogen / Lindlar / CH2Cl2 9.1: 78 percent / aq. cerium ammonium nitrate / acetonitrile / 3 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 1 p. 115 - 134
反应条件
1.1: TiCl4; (iPr)2NEt / CH2Cl2 / 2 h / 0 °C 1.2: 73 percent / CH2Cl2 / 3 h / -78 °C 2.1: 240 mg / aq. HCl / tetrahydrofuran / 14 h / 20 °C 3.1: 92 percent / camphor-10-sulfonic acid / 20 °C 4.1: pyridine / CH2Cl2 / 1 h / -20 °C 5.1: 45 mg / [15]crown-5 ether / tetrahydrofuran / 20 °C 6.1: 70 percent / Mo[N-(tBu)(3,5-dimethylphenyl)]3 / toluene / 20 h / 80 °C 7.1: 100 percent / hydrogen / Lindlar / CH2Cl2 8.1: 78 percent / aq. cerium ammonium nitrate / acetonitrile / 3 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 1 p. 115 - 134
反应条件
1: pyridine / CH2Cl2 / 1 h / -20 °C 2: 45 mg / [15]crown-5 ether / tetrahydrofuran / 20 °C 3: 70 percent / Mo[N-(tBu)(3,5-dimethylphenyl)]3 / toluene / 20 h / 80 °C 4: 100 percent / hydrogen / Lindlar / CH2Cl2 5: 78 percent / aq. cerium ammonium nitrate / acetonitrile / 3 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 1 p. 115 - 134
反应条件
1: 240 mg / aq. HCl / tetrahydrofuran / 14 h / 20 °C 2: 92 percent / camphor-10-sulfonic acid / 20 °C 3: pyridine / CH2Cl2 / 1 h / -20 °C 4: 45 mg / [15]crown-5 ether / tetrahydrofuran / 20 °C 5: 70 percent / Mo[N-(tBu)(3,5-dimethylphenyl)]3 / toluene / 20 h / 80 °C 6: 100 percent / hydrogen / Lindlar / CH2Cl2 7: 78 percent / aq. cerium ammonium nitrate / acetonitrile / 3 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 1 p. 115 - 134
反应条件
1: 45 mg / [15]crown-5 ether / tetrahydrofuran / 20 °C 2: 70 percent / Mo[N-(tBu)(3,5-dimethylphenyl)]3 / toluene / 20 h / 80 °C 3: 100 percent / hydrogen / Lindlar / CH2Cl2 4: 78 percent / aq. cerium ammonium nitrate / acetonitrile / 3 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 1 p. 115 - 134
反应条件
1: 100 percent / hydrogen / Lindlar / CH2Cl2 2: 78 percent / aq. cerium ammonium nitrate / acetonitrile / 3 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 1 p. 115 - 134
反应条件
1: 70 percent / Mo[N-(tBu)(3,5-dimethylphenyl)]3 / toluene / 20 h / 80 °C 2: 100 percent / hydrogen / Lindlar / CH2Cl2 3: 78 percent / aq. cerium ammonium nitrate / acetonitrile / 3 h View Scheme
参考文献
Chemistry - A European Journal, , vol. 13, # 1 p. 115 - 134
