2-氨基-4,5,6,7-四氢-4-苯并噻唑羧酸乙酯合成路线 （共 3 条）
反应条件
in ethanol T=20°C; 16 h;
参考文献
Marinko, Petra; Kastelic, Joze; Krbavcic, Ales; Kikelj, Danijel
Tetrahedron Letters, 2001 , vol. 42, # 50 p. 8911 - 8913
反应条件
1: 98 percent / Br2 / diethyl ether / 2 h / 20 °C 2: 98 percent / ethanol / 16 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 50 p. 8911 - 8913
反应条件
1: With sulfuric acid; copper(II) sulfate; sodium bromide in water
T=-10°C;
2: With sodium nitrite in water
T=20°C;
参考文献
ELI LILLY AND COMPANY
Patent: WO2004/63155 A1, 2004 ;
Location in patent: Page 91-92 ;
WO 2004/063155 A1
