4-乙氧基-2-氧代-3-丁酸乙酯合成路线 （共 4 条）
反应条件
hydrazine monohydrochloride T=20°C; Reflux;
参考文献
ARENA PHARMACEUTICALS, INC.
Patent: WO2009/123714 A2, 2009 ;
Location in patent: Page/Page column 52 ;
WO 2009/123714 A2
反应条件
hydrazine monohydrochloride T=20°C; Reflux;
参考文献
ARENA PHARMACEUTICALS, INC.
Patent: WO2009/123714 A2, 2009 ;
Location in patent: Page/Page column 52 ;
WO 2009/123714 A2
反应条件
in 1,4-dioxane
T=33 - 36°C; 2 h;
参考文献
EURO-CELTIQUE S.A.
Patent: WO2004/111011 A2, 2004 ;
Location in patent: Page 27; 2 ;
参考文献
Nesi, Rodolfo; Chimichi, Stefano; Scotton, Mirella; Degl'Innocenti, Alessandro; Adembri, Giorgio
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1667 - 1670
