2-氨基-3-甲基-3H-咪唑并喹啉合成路线 （共 28 条）
反应条件
1: 87 percent / (CH3CO)2O / 2 h / Ambient temperature 2: 80.3 percent / LiAlH4 / tetrahydrofuran / 0 °C 3: 80.5 percent / HNO3-H2SO4 / 0.17 h / 0 °C 4: 78 percent / H2 / 10percent Pd-C / acetic acid / 7 h / Ambient temperature 5: methanol / 3 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 30, # 5 p. 1857 - 1859
反应条件
1: 80.5 percent / HNO3-H2SO4 / 0.17 h / 0 °C 2: 78 percent / H2 / 10percent Pd-C / acetic acid / 7 h / Ambient temperature 3: methanol / 3 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 30, # 5 p. 1857 - 1859
反应条件
1: 78 percent / H2 / 10percent Pd-C / acetic acid / 7 h / Ambient temperature 2: methanol / 3 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 30, # 5 p. 1857 - 1859
反应条件
1: 80.3 percent / LiAlH4 / tetrahydrofuran / 0 °C 2: 80.5 percent / HNO3-H2SO4 / 0.17 h / 0 °C 3: 78 percent / H2 / 10percent Pd-C / acetic acid / 7 h / Ambient temperature 4: methanol / 3 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 30, # 5 p. 1857 - 1859
反应条件
1: hydrogen / W2 Raney nickel / ethanol / 1 h 2: 1.8 g / ethanol / 3 h / Heating 3: 2.) potassium permanganate, 3.) sodium, ammonia, ferric chloride / 1.) toluene, reflux, 5 h, 2.) acetic acid, 25 deg C, 1.5 h, 3.) reflux, 8 h View Scheme
参考文献
Synthetic Communications, , vol. 18, # 9 p. 973 - 980
反应条件
ammonia in ethanol T=150°C; 5 h; Yield given;
参考文献
Acta Chemica Scandinavica, , vol. 48, # 10 p. 823 - 830
反应条件
ammonia in ethanol T=150°C; 5 h; Yield given;
参考文献
Acta Chemica Scandinavica, , vol. 48, # 10 p. 823 - 830
反应条件
1: in methanol T=100°C; 2: With polyphosphoric acid T=120°C; 0.5 h;
参考文献
Bella, Maros; Milata, Viktor; Larina, Lyudmila I.
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 2 p. 293 - 296
反应条件
1: 1.8 g / ethanol / 3 h / Heating 2: 2.) potassium permanganate, 3.) sodium, ammonia, ferric chloride / 1.) toluene, reflux, 5 h, 2.) acetic acid, 25 deg C, 1.5 h, 3.) reflux, 8 h View Scheme
参考文献
Synthetic Communications, , vol. 18, # 9 p. 973 - 980
反应条件
in water; diethylene glycol T=140°C; Cyclization; 1 h;
参考文献
Mutagenesis, , vol. 9, # 2 p. 157 - 162
