6-氯咪唑并[1,2-a]吡啶-8-羧酸甲酯合成路线 (共 3 条)
反应条件
in ethanol; water
3 h; Heating;
参考文献
Becker, Daniel P.; Flynn, Daniel L.; Moormann, Alan E.; Nosal, Roger; Villamil, Clara I.; Loeffler, Richard; Gullikson, Gary W.; Moummi, Chafiq; Yang, Dai-C.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1125 - 1139
反应条件
1: 3.2 g / K2CO3 / dimethylformamide / 18 h
2: 26 percent / HCl(gas); tert-butylhypochlorite / methanol
3: 80 percent / ethanol; H2O / 3 h / Heating
View Scheme
参考文献
Becker, Daniel P.; Flynn, Daniel L.; Moormann, Alan E.; Nosal, Roger; Villamil, Clara I.; Loeffler, Richard; Gullikson, Gary W.; Moummi, Chafiq; Yang, Dai-C.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1125 - 1139
反应条件
1: 26 percent / HCl(gas); tert-butylhypochlorite / methanol
2: 80 percent / ethanol; H2O / 3 h / Heating
View Scheme
参考文献
Becker, Daniel P.; Flynn, Daniel L.; Moormann, Alan E.; Nosal, Roger; Villamil, Clara I.; Loeffler, Richard; Gullikson, Gary W.; Moummi, Chafiq; Yang, Dai-C.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1125 - 1139