[1,2,5]噻二唑并[3,4-d]嘧啶-7(3H)-酮合成路线 （共 6 条）
反应条件
(i) (Me3Si)2NH, (reflux), (ii) SOCl2, toluene; Multistep reaction;
参考文献
Meyer,R.B.; Skibo,E.B.
Journal of Medicinal Chemistry, 1979 , vol. 22, p. 944 - 948
反应条件
toluene-4-sulfonic acid
96 h; Heating;
参考文献
Shealy,Y.F.; Clayton,J.D.
Journal of Organic Chemistry, 1963 , vol. 28, p. 1491 - 1495
参考文献
Shealy,Y.F.; Clayton,J.D.
Journal of Organic Chemistry, 1963 , vol. 28, p. 1491 - 1495
参考文献
Shealy,Y.F.; Clayton,J.D.
Journal of Organic Chemistry, 1963 , vol. 28, p. 1491 - 1495
反应条件
ammonia in ethanol
T=80°C; 18 h;
参考文献
Shealy,Y.F.; Clayton,J.D.
Journal of Organic Chemistry, 1964 , vol. 29, p. 2141 - 2145
反应条件
hydrogenchloride
T=100°C;
参考文献
Shealy,Y.F.; Clayton,J.D.
Journal of Organic Chemistry, 1963 , vol. 28, p. 1491 - 1495
