1: 60 percent / dimethylformamide / 1 h / 20 °C 2: 1.) HBr 2.) hydrogen, 10percent Pd on charcoal, (morpholinomethyl)polystyrene / 1.) methanol, 15 min, 20 deg C; glacial acetic acid, 90 min, 20 deg C 2.) chloroform, methanol, 1 h, 40 psi 3: saponification 4: 20 percent / 37 °C / pH=7.4 View Scheme