1: With hydrogenchloride; sodium hypochlorite; potassium bromide in water
T=19.5°C; pH=5.9 - 9; 21 - 21.8 h;
2: With hydrogenchloride in water
pH=2.5 - 3.0; Product distribution / selectivity;
1: Wang resin-bound Fmoc-glycine With piperidine in N,N-dimethyl-formamide
T=20°C;
2: dodecanoyl chloride With N-ethyl-N,N-diisopropylamine in dichloromethane
T=20°C; 1 h;
3: With trifluoroacetic acid in dichloromethane
T=20°C; 48 h;
参考文献
Phoon, Chee Wee; Somanadhan, Brinda; Heng, Sabrina Cher Hui; Ngo, Anna; Ng, Siew Bee; Butler, Mark S.; Buss, Antony D.; Sim, Mui Mui
Tetrahedron, 2004 , vol. 60, # 50 p. 11619 - 11628
