3-(1H-苯并咪唑-2-基)苯胺合成路线 （共 12 条）
参考文献
Brana; Castellano; Yunta
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 5 p. 1177 - 1180
反应条件
1: 3-nitro-benzaldehyde With sodium bisulfate in N,N-dimethyl-formamide 1 h; Reflux; 2: 1,2-diamino-benzene in N,N-dimethyl-formamide 3 h; Reflux;
参考文献
TRAGEX PHARMA; HADJ-SLIMANE, Reda; GARBAY, Christiane
Patent: WO2012/156289 A1, 2012 ;
Location in patent: Page/Page column 31-32 ;
反应条件
hydrogenchloride; iron in ethanol; water 3 h; Reflux;
参考文献
Buettner, Anita; Seifert, Katrin; Cottin, Thomas; Sarli, Vasiliki; Tzagkaroulaki, Lito; Scholz, Stefan; Giannis, Athanassios
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 14 p. 4943 - 4954
反应条件
2: tin dichloride; crude hydrochloric acid View Scheme
参考文献
Chemische Berichte, , vol. 34, p. 2963
反应条件
1: toluene-4-sulfonic acid / para-xylene / 18 h / 140 °C / Inert atmosphere 2: 10 palladium on activated carbon; hydrogen / ethanol / 5.5 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 53, # 21 p. 7664 - 7674
反应条件
1: pyridine; 4-(N,N-dimethlyamino)pyridine / 0.25 h / 60 °C / Microwave irradiation; Inert atmosphere 2: toluene-4-sulfonic acid / para-xylene / 18 h / 140 °C / Inert atmosphere 3: 10 palladium on activated carbon; hydrogen / ethanol / 5.5 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 53, # 21 p. 7664 - 7674
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Chemische Berichte, , vol. 34, p. 2963
反应条件
2: tin dichloride; crude hydrochloric acid View Scheme
参考文献
Chemische Berichte, , vol. 34, p. 2963
反应条件
1: diluted alcohol; hydrochloric acid / 40 °C 2: alcoholic ammonium sulfide / 100 °C View Scheme
参考文献
Chemische Berichte, , vol. 32, p. 900
反应条件
1: diluted alcohol; hydrochloric acid / 40 °C 2: alcoholic ammonium sulfide / 100 °C View Scheme
参考文献
Chemische Berichte, , vol. 32, p. 900
