三甲基((2-硝基苯基)乙炔)硅烷合成路线 （共 14 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine in toluene T=20°C; 12 h; Inert atmosphere;
参考文献
Owczarczyk, Zbyslaw R.; Braunecker, Wade A.; Garcia, Andres; Larsen, Ross; Nardes, Alexandre M.; Kopidakis, Nikos; Ginley, David S.; Olson, Dana C.
Macromolecules, 2013 , vol. 46, # 4 p. 1350 - 1360
反应条件
1: KOH / methanol / 1 h 2: (Ph3P)2PdCl2, CuI, Et3N View Scheme
参考文献
ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD.; AHN, Hee Choon; CHO, Young Jun; KWON, Hyuck Joo; KIM, Bong Ok; KIM, Sung Min
Patent: WO2011/132866 A1, 2011 ;
反应条件
1: KOH / methanol / 1 h 2: (Ph3P)2PdCl2, CuI, Et3N 3: 85 percent / aq. KMnO4, AcOH, Adogen 464 / CH2Cl2 / 5 h / Heating View Scheme
参考文献
Journal of the American Chemical Society, , vol. 116, # 18 p. 8152 - 8161
反应条件
5 Au/Fe2O3; hydrogen in toluene T=60 - 120°C; P=750.075 - 15001.5 Torr; 2 h; Autoclave; chemoselective reaction;
参考文献
Yamane, Yoshihiro; Liu, Xiaohao; Hamasaki, Akiyuki; Ishida, Tamao; Haruta, Masatake; Yokoyama, Takushi; Tokunaga, Makoto
Organic Letters, 2009 , vol. 11, # 22 p. 5162 - 5165
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine in N,N-dimethyl-formamide
T=50°C; Sonogashira reaction; 2 h;
参考文献
Mitsumori, Susumu; Honma, Tsunetoshi; Tsuri, Tatsuo; Hiramatsu, Yoshiharu; Okada, Toshihiko; Hashizume, Hiroshi; Inagaki, Masanao; Arimura, Akinori; Yasui, Kiyoshi; Asanuma, Fujio; Kishino, Junji; Ohtani, Mitsuaki
Journal of Medicinal Chemistry, 2003 , vol. 46, # 12 p. 2436 - 2445
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride
T=20°C; 48 h;
参考文献
BAYER CROPSCIENCE AKTIENGESELLSCHAFT
Patent: WO2005/49624 A1, 2005 ;
Location in patent: Page/Page column 32 ;
反应条件
1: With dichloro bis(triphenylphosphine)palladium (II); copper monoiodide; trimethylsilylacetylene in tetrahydrofuran; 1,4-dioxane
T=50 - 80°C; Combinatorial reaction / High throughput screening (HTS);
2: in tetrahydrofuran; 1,4-dioxane; ethyl acetate
参考文献
RIGEL PHARMACEUTICALS, INC.
Patent: WO2004/18463 A2, 2004 ;
Location in patent: Page 61-62 ;
反应条件
copper monoiodide in diethyl ether; water; ethyl acetate; triethylamine
参考文献
Bayer Cropscience Aktiengesellschaft
Patent: US2007/191454 A1, 2007 ;
反应条件
1: KOH / methanol / 1 h
2: (Ph3P)2PdCl2, CuI, Et3N
3: 85 percent / aq. KMnO4, AcOH, Adogen 464 / CH2Cl2 / 5 h / Heating
4: SnCl2*H2O
View Scheme
参考文献
Owczarczyk, Zbyslaw R.; Braunecker, Wade A.; Garcia, Andres; Larsen, Ross; Nardes, Alexandre M.; Kopidakis, Nikos; Ginley, David S.; Olson, Dana C.
Macromolecules, 2013 , vol. 46, # 4 p. 1350 - 1360
反应条件
potassium hydroxide in methanol
1 h; Ambient temperature;
参考文献
Takahashi, S.; Kuroyama, Y.; Sonogashira, K.; Hagihara, N.
Synthesis, 1980 , # 8 p. 627 - 630
