alpha,alpha,2-三甲基苄醇合成路线 （共 27 条）
反应条件
copper oxide-chromium oxide T=100°C; P=88260.9 Torr; Hydrogenation;
参考文献
Birch et al.
Journal of the American Chemical Society, 1949 , vol. 71, p. 1362,1366
反应条件
palladium diacetate; caesium carbonate; triphenylphosphine in o-xylene 24 h; Heating;
参考文献
Terao, Yoshito; Wakui, Hiroyuki; Nomoto, Michiyo; Satoh, Tetsuya; Miura, Masahiro; Nomura, Masakatsu
Journal of Organic Chemistry, 2003 , vol. 68, # 13 p. 5236 - 5243
反应条件
palladium diacetate; caesium carbonate; tri-cyclo-hexyl-phosphine in o-xylene 28 h; Heating;
参考文献
Terao, Yoshito; Wakui, Hiroyuki; Nomoto, Michiyo; Satoh, Tetsuya; Miura, Masahiro; Nomura, Masakatsu
Journal of Organic Chemistry, 2003 , vol. 68, # 13 p. 5236 - 5243
反应条件
1: oxalic acid 2: KMnO4 View Scheme
参考文献
Tiffeneau
Annales de Chimie (Cachan, France), 1907 , vol. <8>10, p. 190
Annales de Chimie (Cachan, France), 1907 , vol. <8>11, p. 144
反应条件
1: in tetrahydrofuran
T=-5 - 20°C; Inert atmosphere;
2: With ammonium chloride in tetrahydrofuran
参考文献
SHANDONG NEW TIME PHARMACEUTICAL CO. LTD.
Patent: US2012/165535 A1, 2012 ;
Location in patent: Page/Page column 5 ;
反应条件
in tetrahydrofuran
T=-5 - 20°C; Inert atmosphere;
参考文献
SHANDONG NEW TIME PHARMACEUTICAL CO. LTD.
Patent: US2012/165535 A1, 2012 ;
Location in patent: Page/Page column 5 ;
参考文献
Tiffeneau
Annales de Chimie (Cachan, France), 1907 , vol. <8>10, p. 190
Annales de Chimie (Cachan, France), 1907 , vol. <8>11, p. 144
参考文献
Ramart; Hoch
Bulletin de la Societe Chimique de France, 1938 , vol. <5> 5, p. 848,860
Show Details
Tiffeneau
Annales de Chimie (Cachan, France), 1907 , vol. <8>10, p. 190
Annales de Chimie (Cachan, France), 1907 , vol. <8>11, p. 144
反应条件
1: H2 / Raney-Ni / hexane / 75006 Torr / Ambient temperature
2: 1.) O2, (PhCO)2O2, 2.) LiAlH4 / 1.) 125 deg C
View Scheme
参考文献
Heinze, Antje; Lauterbach, Gerlinde; Pritzkow, Wilhelm; Schmidt-Renner, Wolfgang; Voerckel, Volkmar; Zewegsuren, Nansadyn
Journal fuer Praktische Chemie (Leipzig), 1987 , vol. 329, # 3 p. 439 - 446
反应条件
1: H3PO4 / H2O / 4 h / Heating
2: 1) Li, naphthalene, 2) H2O / 1) THF, -20 deg C, 12 h
View Scheme
参考文献
Azzena, Ugo; Demartis, Salvatore; Melloni, Giovanni
Journal of Organic Chemistry, 1996 , vol. 61, # 15 p. 4913 - 4919
