3-(4-氯苯基)丙二醛合成路线 （共 26 条）
反应条件
C24H23Cl3P2Pt; hydrogen; tin(ll) chloride in toluene T=50°C; P=30003 Torr; 96 h; AutoclaveInert atmosphere; chemoselective reaction;
参考文献
Journal of Organometallic Chemistry, , vol. 696, # 10 p. 2234 - 2237
反应条件
tetrabutyl-ammonium chloride; sodium hydrogencarbonate; palladium diacetate in N,N-dimethyl-formamide T=25°C; 24 h;
参考文献
Jeffery, Tuyet
Journal of the Chemical Society, Chemical Communications, 1984 , # 19 p. 1287 - 1289
反应条件
methyl diphenyl silane; trimesitylphosphane; bis(dibenzylideneacetone)-palladium(0) in toluene T=60°C; 1.5 h; Schlenk techniqueInert atmosphere;
参考文献
Fujihara, Tetsuaki; Cong, Cong; Iwai, Tomohiro; Terao, Jun; Tsuji, Yasushi
Synlett, 2012 , vol. 23, # 16 art. no. ST-2012-U0571-L, p. 2389 - 2392
反应条件
pyridine; chromium(VI) oxide in dichloromethane 0.25 h; Ambient temperature;
参考文献
Goosen, Andre; Marais, Charles F.; McCleland, Cedric W.; Rinaldi, Fabrizio C.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1995 , # 6 p. 1227 - 1236
反应条件
[rhodium(I)(carbonyl)2(acetylacetonate)]; hydrogen; (R,S)-Binaphos in benzene T=60°C; P=38000 Torr; 34 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Nozaki, Kyoko; Sakai, Nozomu; Nanno, Tetsuo; Higashijima, Takanori; Mano, Satoshi; Horiuchi, Toshihide; Takaya, Hidemasa
Journal of the American Chemical Society, 1997 , vol. 119, # 19 p. 4413 - 4423
反应条件
hydrogen; [rhodium(I)(carbonyl)2(acetylacetonate)]; (R,S)-Ph2P-binaphthyl-cyclic binaphthylphosphoramidite in benzene T=60°C; P=15200 Torr; 24 h;
参考文献
Journal of the American Chemical Society, , vol. 128, # 22 p. 7198 - 7202
反应条件
1: With methyl-diethoxy-silane; Rh(t-Bu-Phebox)(OAc)2(aq) in toluene T=60°C; 2: With potassium fluoride; tetrabutyl ammonium fluoride in tetrahydrofuran; methanol; toluene Further stages.;
参考文献
Kanazawa, Yoshinori; Nishiyama, Hisao
Synlett, 2006 , # 19 p. 3343 - 3345
反应条件
[Rh(acac)2(CO)2]; hydrogen; triphenylphosphine in methanol; toluene T=65°C; P=18751.9 Torr; 0.966667 h; regioselective reaction;
参考文献
Kasinathan, Sivarajan; Bourne, Samuel L.; Tolstoy, Paeivi; Koos, Peter; Obrien, Matthew; Bates, Roderick W.; Baxendale, Ian R.; Ley, Steven V.
Synlett, 2011 , # 18 p. 2648 - 2651
反应条件
1: With methyl-diethoxy-silane; Rh<(S,S)-Phebox-i-Pr>(OAc)2(aq) in toluene T=60°C; 2: With potassium fluoride; tetrabutyl ammonium fluoride in tetrahydrofuran; methanol; toluene Further stages.;
参考文献
Synlett, , # 19 p. 3343 - 3345
反应条件
1: With sodium tetrahydroborate; acetic acid in dichloromethane T=20°C; 1 h; Inert atmosphere; 2: With phenyl silane; triethylamine in tetrahydrofuran T=20°C; 2 h; Inert atmosphere;
参考文献
European Journal of Medicinal Chemistry, , vol. 47, # 1 p. 125 - 137
