2-甲基-2-(2-甲基丁-3-烯-2-基)-1,3-噻唑烷合成路线 (共 3 条)
反应条件
in ethanol; water
20 h; Ambient temperature;
参考文献
Mesnard; Miginiac; Fatome; et al.
European Journal of Medicinal Chemistry, 1980 , vol. 15, # 3 p. 247 - 252
反应条件
magnesium
1.) ether, 0-5 deg C, 1.5 h; 2.) ether, 20 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Laduranty, J.; Barbot, F.; Miginiac, L.
Bulletin de la Societe Chimique de France, 1987 , # 5 p. 837 - 841
反应条件
1: conc. HCl / -10 - 0 °C
2: 1.) magnesium / 1.) ether, 0-5 deg C, 2.) ether, 20 deg C, 3 h
View Scheme
参考文献
Laduranty, Joelle; Barbot, Francis; Miginiac, Leone
Bulletin de la Societe Chimique de France, 1989 , # 6 p. 850 - 855