Novozym 435; acylase I from Aspergillus melleus; amano lipase AK from pseudomonas fluorescens; lipase from wheat germ; papaine in toluene T=40°C; 48 h; Enzymatic reaction; Mechanism;

1: methanol With acetyl chloride T=0°C; 0.166667 h; Inert atmosphere; 2: 3-(4'-bromophenyl)propionic acid T=20°C; 2 h; Inert atmosphere;

Co(1,2-bis-(diphenylphosphino)ethane)Cl2; water; zinc(II) chloride in tetrahydrofuran; acetonitrile T=80°C; 12 h; Inert atmosphereSealed tube;

sodium hydride in tetrahydrofuran

bis(cyclopentadienyl)titanium dichloride; manganese; chloro-trimethyl-silane; triphenylphosphine; nickel dichloride in tetrahydrofuran T=50°C; 16 h; Inert atmosphere;

copper(II) sulfate in water; acetic acid 1 h;

1.1: 78 percent / sodium hydrogensulfate; p-hydroquinone; 4-tert-butylcatechol / diethyl ether / 3 h / 200 °C 2.1: BMS / bis-(2-methoxy-ethyl) ether / 3.5 h / 0 - 140 °C 2.2: aq. NaOH; H2O2 / 3 h / 25 - 50 °C 3.1: CrO3; aq. H2SO4 / acetone / 0.5 h / 20 °C 4.1: 80 percent / thionyl chloride / 2 h / Heating View Scheme

1.1: BMS / bis-(2-methoxy-ethyl) ether / 3.5 h / 0 - 140 °C 1.2: aq. NaOH; H2O2 / 3 h / 25 - 50 °C 2.1: CrO3; aq. H2SO4 / acetone / 0.5 h / 20 °C 3.1: 80 percent / thionyl chloride / 2 h / Heating View Scheme

1: CrO3; aq. H2SO4 / acetone / 0.5 h / 20 °C 2: 80 percent / thionyl chloride / 2 h / Heating View Scheme

1.1: 76 percent / diethyl ether / 1 h / 20 °C 2.1: 78 percent / sodium hydrogensulfate; p-hydroquinone; 4-tert-butylcatechol / diethyl ether / 3 h / 200 °C 3.1: BMS / bis-(2-methoxy-ethyl) ether / 3.5 h / 0 - 140 °C 3.2: aq. NaOH; H2O2 / 3 h / 25 - 50 °C 4.1: CrO3; aq. H2SO4 / acetone / 0.5 h / 20 °C 5.1: 80 percent / thionyl chloride / 2 h / Heating View Scheme