4-氨基-1,3-二氢-苯并咪唑-2-酮合成路线 (共 2 条)
反应条件
hydrogen; palladium 10 on activated carbon in tetrahydrofuran; methanol
P=3102.97 Torr;
参考文献
Pharmeste S.r.l.
Patent: EP2377850 A1, 2011 ;
Location in patent: Page/Page column 11 ;
反应条件
1: 97 percent / dimethylsulfoxide
2: 68 percent / H2 / Pd/C / ethanol
View Scheme
参考文献
Mewshaw, Richard E.; Verwijs, Antoine; Shi, Xiaojie; McGaughey, Georgia B.; Nelson, James A.; Mazandarani, Hossein; Brennan, Julie A.; Marquis, Karen L.; Coupet, Joseph; Andree, Terrance H.
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 19 p. 2675 - 2680