1: 92 percent / 0.25 h / Heating 2: 1) LiH / 1) acetonitrile, 40 degC, 2 h, 2) room temp., 24 h 3: 82 percent / HOAc / 60 °C 4: 83.4 percent / H2 / Pd/C (10percent) / ethanol; acetic acid / 1 h 5: 84.9 percent / pyridine / 0.42 h / Ambient temperature View Scheme

1: 1) LiH / 1) acetonitrile, 40 degC, 2 h, 2) room temp., 24 h 2: 82 percent / HOAc / 60 °C 3: 83.4 percent / H2 / Pd/C (10percent) / ethanol; acetic acid / 1 h 4: 84.9 percent / pyridine / 0.42 h / Ambient temperature View Scheme

1: 83.4 percent / H2 / Pd/C (10percent) / ethanol; acetic acid / 1 h 2: 84.9 percent / pyridine / 0.42 h / Ambient temperature View Scheme

1: 82 percent / HOAc / 60 °C 2: 83.4 percent / H2 / Pd/C (10percent) / ethanol; acetic acid / 1 h 3: 84.9 percent / pyridine / 0.42 h / Ambient temperature View Scheme

pyridine 0.416667 h; Ambient temperature;

potassium carbonate in acetone 2.5 h; Ambient temperature;