反应条件
1: 92 percent / trimethylbenzyl ammonium hydroxyde / methanol / 24 h
2: 97 percent / hydrogen / Raney nickel / ethanol / 3 h / 80 °C / 45003.6 Torr
3: 1.) sodium; 2.) 6N HCl / 1.) ethanol, water, 31 deg C, 2h; 2.) water, 60 deg C, 1 h
4: 70 percent / xylene / 0.5 h / Heating
5: 70 percent / CH2Cl2 / 1 h
6: ethanol / 20 h / Heating
View Scheme
参考文献
Maillard; Langlois; Vo Van; et al.
European Journal of Medicinal Chemistry, 1983 , vol. 18, # 4 p. 353 - 358
