L-苯丙氨酸甲酯盐酸盐合成路线 (共 169 条)
反应条件
in chloroform-d1; methanol-d4 Inert atmosphere; Equilibrium constant;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 19 p. 2293 - 2298
反应条件
in chloroform-d1; methanol-d4 Inert atmosphere; Equilibrium constant;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 19 p. 2293 - 2298
反应条件
in chloroform-d1; methanol-d4 Inert atmosphere; Equilibrium constant;
参考文献
Tetrahedron Asymmetry, , vol. 20, # 19 p. 2293 - 2298
反应条件
1: Et3N / CHCl3 2: KOH / methanol; dioxane 3: DCC, Et3N / CHCl3 4: HBr / CHCl3 View Scheme
参考文献
Cosmatos,A. et al.
Chemische Berichte, 1961 , vol. 94, p. 2644 - 2655
反应条件
1.1: sodium carbonate / water; ethyl acetate / 0 - 16 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0.03 h / 0 °C 2.2: 2 h / 20 °C 3.1: lithium hydroxide hydrate / tetrahydrofuran; water / 2 h / 0 - 20 °C View Scheme
参考文献
Sun, Dequn; Zhang, Lingzi; Wang, Jin
Asian Journal of Chemistry, 2012 , vol. 24, # 1 p. 319 - 322
反应条件
1: 74 percent / KHCO3; triethylamine / H2O; CHCl3 / 5 h / 0 °C 2: 95 percent / NaOH / methanol; tetrahydrofuran; H2O / 2 h / 0 °C View Scheme
参考文献
Pal, Asish; Ghosh, Yamuna K.; Bhattacharya, Santanu
Tetrahedron, 2007 , vol. 63, # 31 p. 7334 - 7348
反应条件
sodium tetrahydroborate in ethanol 1.) room temperature, 4 h, 2.) reflux, 6 h, 3.) room temperature, overnight;
参考文献
Meyers,A.I.; Williams,D.R.; Erickson,G.W.
Journal of the American Chemical Society, 1981 , vol. 103, p. 3081
反应条件
1: ethanol / 35 h 2: 78 percent / pentane / Heating 3: HCl / methanol / 1.) 0 deg C, 30 min; 2.) room temp., 2 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 68, p. 135 - 143
反应条件
1: 97 percent 2: 89 percent / LiBH4 / 1,2-dimethoxy-ethane 3: 89 percent / pyridine View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 24, # 5 p. 503 - 510
反应条件
in water; acetonitrile T=37°C; pH=4 - 10; Further byproducts given. Title compound not separated from byproducts;
参考文献
Journal of Agricultural and Food Chemistry, , vol. 52, # 23 p. 7126 - 7131