L-苯丙氨酸甲酯盐酸盐合成路线 （共 169 条）
反应条件
chloro-trimethyl-silane T=20°C; Esterification; de-tert-butoxycarbonylation; 19 h;
参考文献
Journal of Organic Chemistry, , vol. 64, # 25 p. 9294 - 9296
反应条件
chiral stationary phase including isopropyl-functionalized CF6 in ethanol; n-heptane; trifluoroacetic acid T=20°C; Purification / work up;
参考文献
WO2010/148191 A2, ;
Page/Page column 45-49; 59 ;
反应条件
thionyl chloride T=0 - 80°C; 4.5 h;
参考文献
Chemistry - A European Journal, , vol. 19, # 49 p. 16615 - 16624
反应条件
hydrogenchloride Ambient temperature;
参考文献
Journal of the American Chemical Society, , vol. 103, # 14 p. 4231 - 4239
参考文献
Journal of the American Chemical Society, , vol. 79, p. 3827,3830
反应条件
1.1: LDA / tetrahydrofuran / -78 °C 1.2: 85 percent / tetrahydrofuran / -78 °C 2.1: aq. HCl / diethyl ether / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 23 p. 8094 - 8095
反应条件
1: acetyl chloride in methanol Cooling with ice; 2: L-phenylalanine in methanol T=70°C; 24 h; Reflux;
参考文献
European Journal of Organic Chemistry, , # 26 p. 5838 - 5847
反应条件
hydrogenchloride in diethyl ether
参考文献
Journal of the Chemical Society, Chemical Communications, , # 19 p. 1132 - 1133
反应条件
1: 94 percent / dicyclohexylcarbodi-imide, 4-dimethylaminopyridine / 1) 0 deg C, 5 min, 2) 25 deg C, 3 h 2: HCl / diethyl ether View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 19 p. 1132 - 1133
反应条件
hydrogenchloride in water
参考文献
Synlett, , # 17 p. 2803 - 2808
