5-(N-叔丁氧羰基氨基)-1-戊醇合成路线 （共 23 条）
反应条件
in dichloromethane 12 h;
参考文献
Mattingly, Phillip G.
Synthesis, 1990 , p. 366 - 368
反应条件
Cp*RuCl{(C6H5)2P-(CH2)2NH2-κ2-P,N}; potassium tert-butylate; hydrogen in tert-butyl alcohol T=80°C; P=22502.3 Torr; 24 h; Autoclave;
参考文献
Ito, Masato; Koo, Lee Wei; Himizu, Akio; Kobayashi, Chika; Sakaguchi, Ayaka; Ikariya, Takao
Angewandte Chemie - International Edition, 2009 , vol. 48, # 7 p. 1324 - 1327
反应条件
in dichloromethane T=20°C; Cooling with ice;
参考文献
Maharvi, Ghulam M.; Bharucha, Adil E.; Fauq, Abdul H.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 9 p. 2808 - 2811
反应条件
triethylamine in tetrahydrofuran; dichloromethane; chloroform
参考文献
Isis Pharmaceuticals, Inc.
Patent: US6191273 B1, 2001 ;
反应条件
ethanol; copper(ll) bromide T=20°C; 4 h;
参考文献
Mezaache, Rofia; Dembele, Yenimegue Albert; Bikard, Yann; Weibel, Jean-Marc; Blanc, Aurelien; Pale, Patrick
Tetrahedron Letters, 2009 , vol. 50, # 52 p. 7322 - 7326
参考文献
Chemical and pharmaceutical bulletin, , vol. 31, # 9 p. 3360 - 3362
反应条件
1: 82 percent / Ph3P, DEAD / tetrahydrofuran / Ambient temperature 2: 87 percent / Zn, 1.) M aq. KH2PO4 / tetrahydrofuran / 4 h / Ambient temperature 3: 95 percent / H2 / 10percent Pd/C / methanol / 1 h / Ambient temperature View Scheme
参考文献
Arasujo, M. Joso S. M. P.; Ragnarsson, Ulf; Trigo, M. Joaquina S. A. Amaral; Almeida, M. Lurdes S.
Journal of Chemical Research, Miniprint, 1996 , # 8 p. 2143 - 2161
反应条件
triethylamine in dichloromethane T=20°C;
参考文献
METHYLGENE INC.
Patent: WO2006/102760 A1, 2006 ;
Location in patent: Page/Page column 133 ;
反应条件
methanesulfonyl chloride; triethylamine in DCM T=20°C; 1 h;
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2007/71396 A2, 2007 ;
Location in patent: Page/Page column 136 ;
WO 2007/071396 A2
反应条件
sodium chloride in pyridine
参考文献
Sanofi
Patent: US5594023 A1, 1997 ;
