4-苯基-1H-吡唑-3-羧酸合成路线 （共 15 条）
反应条件
sodium hydroxide Erhitzen des Reaktionsgemisches auf 190grad;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. <2> 126, p. 177,192
参考文献
Catiela, Carlos; Villegas, M. Dolores Diaz de; Gainza, M. Pilar
Synthetic Communications, 1987 , vol. 17, # 2 p. 165 - 172
反应条件
water; sodium hydroxide in ethanol
T=120°C; 1 h; Microwave irradiationSealed tube;
参考文献
Ermolenko, Mikhail S.; Guillou, Sandrine; Janin, Yves L.
Tetrahedron, 2013 , vol. 69, # 1 p. 257 - 263
反应条件
1: With potassium hydroxide; water in ethanol
T=150 - 170°C; 0.833333 h; microwave irradiation;
2: With hydrogenchloride; water in ethanol
pH=1;
参考文献
ASTEX THERAPEUTICS LIMITED
Patent: WO2006/77425 A1, 2006 ;
Location in patent: Page/Page column 202 ;
WO 2006/077425 A1
反应条件
potassium permanganate; water
durch Oxidation;
参考文献
Parham; Bleasdale
Journal of the American Chemical Society, 1950 , vol. 72, p. 3843,3844
反应条件
1: diethyl ether
2: aqueous KOH
3: KMnO4; H2O / durch Oxidation
View Scheme
参考文献
Parham; Bleasdale
Journal of the American Chemical Society, 1950 , vol. 72, p. 3843,3844
反应条件
1: aqueous KOH
2: KMnO4; H2O / durch Oxidation
View Scheme
参考文献
Parham; Bleasdale
Journal of the American Chemical Society, 1950 , vol. 72, p. 3843,3844
反应条件
1: CHCl3 / 72 h / Ambient temperature
2: BF3*Et2O / 0.25 h / Heating
3: 10percent KOH / methanol / 0.5 h / 65 °C
View Scheme
参考文献
Catiela, Carlos; Villegas, M. Dolores Diaz de; Gainza, M. Pilar
Synthetic Communications, 1987 , vol. 17, # 2 p. 165 - 172
反应条件
1: BF3*Et2O / 0.25 h / Heating
2: 10percent KOH / methanol / 0.5 h / 65 °C
View Scheme
参考文献
Catiela, Carlos; Villegas, M. Dolores Diaz de; Gainza, M. Pilar
Synthetic Communications, 1987 , vol. 17, # 2 p. 165 - 172
反应条件
1: BF3*Et2O / 0.25 h / Heating
2: 10percent KOH / methanol / 0.5 h / 65 °C
View Scheme
参考文献
Catiela, Carlos; Villegas, M. Dolores Diaz de; Gainza, M. Pilar
Synthetic Communications, 1987 , vol. 17, # 2 p. 165 - 172
