bromine in acetic acid T=20°C; 3 h; Inert atmosphere;

potassium hydroxide; water 36 h; Heating;

1: 87 percent / aq. potassium hydroxide (33percent w/w) 2: 98.7 percent / sodium borohydride / methanol 3: 1.) thionyl chloride, 2.) sodium iodide, H2O / 1.) benzene, 2.5 h, 2.) ethyl methyl ketone, reflux, 3 h 4: 65 percent / sodum acetate, bromine / CHCl3 / 1 h / Ambient temperature 5: 98.4 percent / 0.85N methanolic potassium hydroxide, H2O / 36 h / Heating View Scheme

1: 98.7 percent / sodium borohydride / methanol 2: 1.) thionyl chloride, 2.) sodium iodide, H2O / 1.) benzene, 2.5 h, 2.) ethyl methyl ketone, reflux, 3 h 3: 65 percent / sodum acetate, bromine / CHCl3 / 1 h / Ambient temperature 4: 98.4 percent / 0.85N methanolic potassium hydroxide, H2O / 36 h / Heating View Scheme

1: 1.) thionyl chloride, 2.) sodium iodide, H2O / 1.) benzene, 2.5 h, 2.) ethyl methyl ketone, reflux, 3 h 2: 65 percent / sodum acetate, bromine / CHCl3 / 1 h / Ambient temperature 3: 98.4 percent / 0.85N methanolic potassium hydroxide, H2O / 36 h / Heating View Scheme

1: 65 percent / sodum acetate, bromine / CHCl3 / 1 h / Ambient temperature 2: 98.4 percent / 0.85N methanolic potassium hydroxide, H2O / 36 h / Heating View Scheme