4,4-二苯基-3-丁烯酸合成路线 （共 33 条）
参考文献
Boyce,R. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1974 , p. 792 - 796
反应条件
1: 9.2 g / H2 / palladium on charcoal / methanol / 3 h / 710 Torr
2: 7.6 g / polyphosphoric acid / 1 h / 90 °C
3: 4.8 g / sodium borohydride / ethanol
4: 70 percent / phosphoric acid / 2 h / 120 - 130 °C
View Scheme
参考文献
Kopecky, Karl R.; Hall, Michael C.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 3095 - 3104
反应条件
acetic anhydride in acetic acid
0.5 h; Heating;
参考文献
Kurosawa, Kazu; Tsujita, Tsuyoshi
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 8 p. 2391 - 2394
反应条件
1.1: 72 percent / H2SO4 / CH2Cl2 / 2.5 h / Heating
2.1: LDA / tetrahydrofuran; hexane / 0.17 h / -78 °C
2.2: 66 percent / tetrahydrofuran; hexane / 18 h / 20 °C
3.1: 72 percent / LiAlH4 / diethyl ether / 1 h / 20 °C
4.1: 93 percent / PCC / CH2Cl2 / 1.25 h / 20 °C
5.1: 25 percent / m-methoxyacetophenone / CH2Cl2 / 7 h / Irradiation
View Scheme
参考文献
Armesto; Ortiz; Agarrabeitia; Aparicio-Lara
Synthesis, 2001 , # 8 p. 1149 - 1158
反应条件
hydrogen; palladium on activated charcoal in sodium hydroxide
P=1838.8 Torr; 6 h;
参考文献
Kansal, V. K.; Bhaduri, A. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 10 p. 885 - 890
反应条件
phosphorus; phosphoric acid; potassium iodide
参考文献
Dippy; Young
Journal of the Chemical Society, 1955 , p. 3919,3922
反应条件
1: bromine; water
2: pyridine
View Scheme
参考文献
Newman; Joshel; Wise
Journal of the American Chemical Society, 1940 , vol. 62, p. 1861
反应条件
diethyl ether
Erwaermen des Reaktionsprodukts mit LiAlH4 in Aether;
参考文献
Graham; Williams
Journal of the Chemical Society, 1959 , p. 4066,4072
反应条件
sulfuric acid
0.5 h; Ambient temperature;
参考文献
Katritzky, Alan R.; Feng, Daming; Lang, Hengyuan
Journal of Organic Chemistry, 1997 , vol. 62, # 12 p. 4131 - 4136
参考文献
Johnson; Petersen; Schneider
Journal of the American Chemical Society, 1947 , vol. 69, p. 74,77
