2-氯-1,1,1-三甲氧基乙烷合成路线 （共 30 条）
反应条件
sodium methylate; chlorine T=15°C; 4 h;
参考文献
Degussa AG
Patent: EP1371624 A1, 2003 ;
Location in patent: Page 3 ;
反应条件
sulfuric acid in methanol T=20°C;
参考文献
Tetrahedron Letters, , vol. 54, # 19 p. 2366 - 2368
参考文献
Cowden; Wilson; Bishop; Cottrell; Davies; Dolling
Tetrahedron Letters, 2000 , vol. 41, # 44 p. 8661 - 8664
反应条件
sodium T=60 - 70°C; 3 h;
参考文献
Russian Journal of Organic Chemistry, , vol. 29, # 12 p. 1981 - 1988
Zhurnal Organicheskoi Khimii, , vol. 29, # 12 p. 2375 - 2385
参考文献
BIOTA EUROPE LTD.
Patent: US2010/298388 A1, 2010 ;
Location in patent: Page/Page column 7 ;
参考文献
PROLYSIS LTD
Patent: WO2007/107758 A1, 2007 ;
Location in patent: Page/Page column 88-89 ;
WO 2007/107758 A1
参考文献
Boehringer Ingelheim Pharma GmbH and Co. KG
Patent: US2004/209865 A1, 2004 ;
US 20040209865 A1
反应条件
in toluene T=200°C; 16 h; Inert atmosphere;
参考文献
Lee, Jennifer J.; Kraus, George A.
Tetrahedron Letters, 2013 , vol. 54, # 19 p. 2366 - 2368
反应条件
T=160°C; 0.0833333 h; microwave irradiation;
参考文献
Synthetic Communications, , vol. 34, # 14 p. 2523 - 2529
反应条件
1: With acetic acid 24 h; Reflux; 2: With sulfuric acid T=100°C; 2 h; 3: With potassium carbonate in water
参考文献
ARGENTA DISCOVERY LIMITED; ASTRAZENECA AB
Patent: WO2009/153536 A1, 2009 ;
Location in patent: Page/Page column 41-42 ;
WO 2009/153536 A1
