1: With n-butyllithium in tetrahydrofuran; hexane T=-105 - 20°C; 2: With sodium chlorite; potassium dihydrogenphosphate in tert-butyl alcohol T=20°C; Lindgren oxidation; 90 h; Title compound not separated from byproducts;

1.1: n-BuLi / tetrahydrofuran; hexane / -105 - 20 °C 1.2: aq. NaClO2; KH2PO4 / 2-methyl-propan-2-ol; various solvent(s) / 90 h / 20 °C 2.1: borane-dimethyl sulfide complex / diethyl ether / 1 h / 0 - 20 °C View Scheme