6-氯-2-甲氧基-9-苯氧基吖啶合成路线 (共 20 条)
反应条件
sodium hydroxide T=100°C; 2 h;
参考文献
Ross, Steven A.; Pitie, Marguerite; Meunier, Bernard
European Journal of Inorganic Chemistry, 1999 , # 3 p. 557 - 563
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Inhoff, Oliver; Richards, Jonathan M.; Briet, Jan Willem; Lowe, Gordon; Krauth-Siegel, R. Luise
Journal of Medicinal Chemistry, 2002 , vol. 45, # 20 p. 4524 - 4530
反应条件
1,4-diaza-bicyclo[2.2.2]octane 1) room temp., 15 min., DMSO; 2) 70 deg C, 18 h; Yield given. Multistep reaction;
参考文献
Constant; Carden; Lhomme
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 4 p. 1035 - 1040
反应条件
in N,N-dimethyl-formamide T=80°C; 4 h;
参考文献
Constant; Carden; Lhomme
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 4 p. 1035 - 1040
反应条件
in N,N-dimethyl-formamide T=110°C; 12 h; Yield given;
参考文献
Constant; Carden; Lhomme
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 4 p. 1035 - 1040
反应条件
in N,N-dimethyl-formamide T=80°C; 4 h; Yield given;
参考文献
Constant; Carden; Lhomme
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 4 p. 1035 - 1040
反应条件
in N,N-dimethyl-formamide T=110°C; 10 h; Yield given;
参考文献
Constant; Carden; Lhomme
Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 4 p. 1035 - 1040
参考文献
Drosdow
Zhurnal Obshchei Khimii, 1937 , vol. 7, p. 2292,2295
Chem. Zentralbl., 1938 , vol. 109, # I p. 602
反应条件
beim Erhitzen in saurer Loesung;
参考文献
Drosdow
Zhurnal Obshchei Khimii, 1937 , vol. 7, p. 2292,2295
Chem. Zentralbl., 1938 , vol. 109, # I p. 602
反应条件
1: phenol
2: HCl / acetic acid
View Scheme
参考文献
Hansen, John B.; Buchardt, Ole
Journal of the Chemical Society, Chemical Communications, 1983 , # 4 p. 162 - 164
参考文献
Hansen, John B.; Buchardt, Ole
Journal of the Chemical Society, Chemical Communications, 1983 , # 4 p. 162 - 164