sodium hydroxide; chloroform in dichloromethane T=25°C; 36 h;

1: With ethylmagnesium bromide in tetrahydrofuran T=-78°C; Inert atmosphere; 2: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.0833333 h; Inert atmosphere; 3: With methanol; sodium methylate in tetrahydrofuran; hexane 1 h; Inert atmosphereReflux;

lead(IV) acetate; iodine in benzene Irradiationa) room temp., 15 min, b) reflux, 2.5 h;

N,N-di-methylaminopyridine in dichloromethane; N,N-dimethyl-formamide; benzene

1-iodo-2,2,2-trifluoroethane; Fonderma; 4-(N,N-dimethlyamino)pyridine in benzene 0.5 h; HeatingIrradiation; Yield given;

sodium hydroxide; chloroform in dichloromethane T=25°C; 192 h; Title compound not separated from byproducts.;