1-(4-甲氧基苯基)-1-环己烷羧酸合成路线 （共 3 条）
反应条件
1: With sodium hydroxide; dihydrogen peroxide in trans-1,3-dioxane; water
96 h; Heating / reflux;
2: With hydrogenchloride in trans-1,3-dioxane; water
pH=1;
参考文献
TOPOTARGET UK LIMITED
Patent: WO2004/65354 A1, 2004 ;
Location in patent: Page 103; 104; 115; 71; 75 ;
反应条件
sodium hydroxide; diethyl ether
参考文献
Tchoubar
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1952 , vol. 234, p. 2544
反应条件
oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane
T=20 - 40°C; 1.25 h;
参考文献
TOPOTARGET UK LIMITED
Patent: WO2004/65354 A1, 2004 ;
Location in patent: Page 108; 128; 129; 73; 79 ;
