4-哌啶甲酸甲酯盐酸盐合成路线

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Alfaro-Lopez, Josue; Okayama, Toru; Hosohata, Keiko; Davis, Peg; Porreca, Frank; Yamamura, Henry I.; Hruby, Victor J.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5359 - 5368

498-94-24-哌啶甲酸

7462-86-44-哌啶甲酸甲酯盐酸盐

参考文献

US6069143 A1, ;

7462-86-44-哌啶甲酸甲酯盐酸盐

67686-01-51-苄基-4-哌啶甲醇

参考文献

Alfaro-Lopez, Josue; Okayama, Toru; Hosohata, Keiko; Davis, Peg; Porreca, Frank; Yamamura, Henry I.; Hruby, Victor J.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5359 - 5368

7462-86-44-哌啶甲酸甲酯盐酸盐+

1538-75-6三甲基乙酸酐

124443-68-1N-Boc-4-哌啶甲酸甲酯

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Carr, Albert A.; Hay, David A.; Kane, John M.; Staeger, Michael A.
Journal of Organic Chemistry, 1990 , vol. 55, # 4 p. 1399 - 1401

124443-68-1N-Boc-4-哌啶甲酸甲酯

参考文献

Dompe Farmaceutici S.p.A.
Patent: US5656656 A1, 1997 ;

7462-86-44-哌啶甲酸甲酯盐酸盐+

100-39-0溴化苄

10315-06-71-苄基-4-哌啶甲酸甲酯

参考文献

Alfaro-Lopez, Josue; Okayama, Toru; Hosohata, Keiko; Davis, Peg; Porreca, Frank; Yamamura, Henry I.; Hruby, Victor J.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5359 - 5368

7462-86-44-哌啶甲酸甲酯盐酸盐

22065-85-61-苄基-4-哌啶甲醛

参考文献

Alfaro-Lopez, Josue; Okayama, Toru; Hosohata, Keiko; Davis, Peg; Porreca, Frank; Yamamura, Henry I.; Hruby, Victor J.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5359 - 5368

7462-86-44-哌啶甲酸甲酯盐酸盐

42596-58-7哌啶-4-碳酰肼

参考文献

Fox; Gibas
Journal of Organic Chemistry, 1953 , vol. 18, p. 994,1001

7462-86-44-哌啶甲酸甲酯盐酸盐+

3282-30-2三甲基乙酰氯

505088-49-31-特戊酰哌啶-4-羧酸甲酯

参考文献

NEWLINK GENETICKS CORPORATION; MAUTINO, Mario; KUMAR, Sanjeev; WALDO, Jesse; JAIPURI, Firoz; KESHARWANI, Tanay
Patent: WO2012/142237 A1, 2012 ;
Location in patent: Page/Page column 100 ;
WO 2012/142237 A1