反应条件
1: 1.) MeOTf, 2.) L-Selectride / 1,) CH2Cl2, RT, 2.) THF, -78 deg C 2: 5A molecular sieves 3: Heating 4: 82 percent / KOH / methanol 5: 93 percent / DMSO, (COCl)2 / CH2Cl2 / -60 °C 6: 92 percent / 1,2-dimethoxy-ethane / 0 °C 7: (S)-BINAL-H / tetrahydrofuran / -100 - -78 °C 8: 1.) m-CPBA, 2.) NH4Cl, H2O / 1.) CH2Cl2, 0 deg C 9: 72 percent / 0.1 M phosphate buffer / Baker's yeast, pH 7.0 View Scheme
参考文献
Journal of the American Chemical Society, , vol. 114, # 8 p. 3125 - 3126
