(S)-2-(3-(叔丁氧羰基氨基)-2-氧代哌啶-1-基)乙酸合成路线 （共 7 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol P=1551.4 Torr;
参考文献
Semple; Rowley; Brunck; Ha-Uong; Minami; Owens; Tamura; Goldman; Siev; Ardecky; Carpenter; Ge; Richard; Nolan; Hakanson; Tulinsky; Nutt; Ripka
Journal of Medicinal Chemistry, 1996 , vol. 39, # 23 p. 4531 - 4536
反应条件
in N,N-dimethyl-formamide T=55°C; 2 h;
参考文献
Freidinger, Roger M.; Perlow, Debra Schwenk; Veber, Daniel F.
Journal of Organic Chemistry, 1982 , vol. 47, # 1 p. 104 - 109
反应条件
1: H2; aq. AcOH / 10 percent Pd/C / methanol / 2327.17 Torr 2: methanol / 60 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 4 p. 723 - 728
反应条件
1: 80 percent / EDC, HOBt, NMM / acetonitrile / Ambient temperature 2: 85 percent / LiHMDS / tetrahydrofuran / Ambient temperature 3: 100 percent / H2 / Pd/C / ethanol / 1551.4 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 23 p. 4531 - 4536
反应条件
1: 85 percent / LiHMDS / tetrahydrofuran / Ambient temperature 2: 100 percent / H2 / Pd/C / ethanol / 1551.4 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 23 p. 4531 - 4536
反应条件
Yield given. Multistep reaction;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 18 p. 2421 - 2426
反应条件
potassium carbonate in N,N-dimethyl-formamide; acetonitrile Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 24 p. 3525 - 3530
